Nurjana, Susiati (2021) EFEKTIFITAS FRAKSI ETIL ASETAT EKSTRAK DAUN PEPAYA (Carica Papaya L.) SEBAGAI ANTIMALARIA TERHADAP PLASMODIUM FALCIPARUM: NARRATIVE REVIEW. Other thesis, Skripsi, Universitas Muhammadiyah Magelang.
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Abstract
Malaria is a life-threatening disease caused by a parasite that is transmitted to humans through the bite of an infected female Anopheles mosquito. The number of deaths from malaria reached 405,000. A total of 67% (272,000) cases of malaria deaths were from children (<5 years). The antimalarial and antiplasmodial activity was shown by the extract of papaya leaves. The aim of this review is to see the effectiveness of the acetate fraction of papaya leaf extract as an antimalarial to plasmodium falciparum. This study used a narrative review study method with 9 research articles on the Carica Papaya L. leaf plant as an antimalarial to Plasmodium falciparum in the last 10 years. The data search in this review uses data based on google scholar and semantic scholar with the keyword "Antimalarial AND Solvent Fractions AND Papaya AND Plasmodium; Antimalarials AND Extracts AND Carica papaya AND Plasmodium; Mechanisms AND Antimalarials AND Ingredients AND Papaya Leaves ". The results showed that papaya leaf extract (carica papaya L.) had antimalarial activity of plasmodium falciparum. The content of compounds in papaya leaves includes alkaloids, flavonoids, saponins, tannins and glycolysis. Flavonoids have been reported to exhibit significant in vitro antimalarial activity against P. falciparum. It is necessary to carry out further studies related to the findings of more specific flavonoid compounds from papaya leaf extract.
| Item Type: | Karya Ilmiah (Other) |
|---|---|
| Pembimbing: | apt. Setiyo Budi Santoso, M.Farm dan apt. Elmiawati Lathifah, M.Sc |
| Uncontrolled Keywords: | Antimalarial, Plasmodium Falciparum, Papaya Leaves, Flavonoids, Ethyl Acetate Fraction. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Depositing User: | Atin Istiarni |
| Date Deposited: | 06 Oct 2021 04:34 |
| Last Modified: | 07 Oct 2021 02:47 |
| URI: | http://eprintslib.ummgl.ac.id/id/eprint/2640 |
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